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It was found that naltrexone and bupropion combined, which might be marketed in the future as Contrave, have better weight loss results than diet and exercise alone. Using two separate drugs to shed weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you need to err assisting caution and permit the FDA do its job and demand some study be done so that the public is aware of the side effects and risks of the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say anything to keep people on their medications. Researchers discovered that participants taking this drug for a year, lost excess weight within one month and have kept the weight off through the 56 weeks with the study. Contrave is really a combination of the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which can be made up of many active ingredient, which can make them more effective and safer. Combo-pilling could be the newest fad or better yet the newest into the future under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular may be the fact that since right now there are not any long term prescription weight loss supplements that have been authorized by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and must not be taken in people with seizure disorders. The drug could also raise blood pressure and heart rate, and must not be used in people with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure level and heart rate and must 't be used in patients with uncontrolled high blood pressure level, as well as by a person with heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients to the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking. --Participating in support groups that help the family of the addict recover (for example Al-Anon or Nar-Anon).